

Is osteopathic treatment appropriate for a patient with multimorbidity?
https://doi.org/10.32885/2220-0975-2025-3-123-133
Abstract
Multimorbidity is the coexistence of two or more chronic diseases in the same person, without prioritization, in contrast to comorbidity, where the main disease is highlighted. Multimorbidity increases the burden of medication, significantly impairing the quality of life of patients, which prompts the search for additional non-drug methods of care. Osteopathic correction can have a positive effect on the main pathogenetic links of diseases, among which are biomechanical and neurogenic manifestations of somatic dysfunction (SD), as well as on emotionalaffective disorders, functional disorders of segmental and suprasegmental autonomic structures, nociceptive and antinociceptive systems. In the treatment of patients with diseases of the nervous system, the literature notes the effectiveness of osteopathic correction in a comprehensive approach, including those confirmed by neurophysiological and neuroimaging methods. However, data regarding the effectiveness of osteopathic treatment in multimorbid patients are insufficient. We present a clinical case demonstrating the possibilities of osteopathic treatment in a patient with multimorbidity — with focal reflex epilepsy, classical migraine with aura, combined with chronic tension headache and nonspecific chronic musculoskeletal pain. Each of her chronic conditions requires medication intervention: focal reflex epilepsy — constant administration of anticonvulsant medication, migraine attacks, chronic tension headache and musculoskeletal pain — management with non-steroidal anti-inflammatory drugs and/or analgesics. Also background — anxiety is noted, she is consulted by a psychologist and periodically takes anxiolytics (tranquilizers). In our opinion, among the complex of factors contributing to the realization of diseases of the nervous system, including epilepsy, trigeminovascular syndromes, chronic tension headache, chronic musculoskeletal pain in the neck and upper back, there may be morphological and functional features of the skull and associated tissues and structures, in addition to the main and other causes. In the present clinical case, the patient had several regional SD identified on osteopathic examination. The dominant biomechanical disorder is the head region SD, and in the structure of this regional disorder the most attention was attracted by: SD of the sphenobasillary synchondrosis of the lateroflexion with rotation (SBR) type and SD of the right temporal bone. The first osteopathic procedure with correction of the head region in general and the temporal bone in particular resulted in a significant improvement of the patient′s condition. Background headache, pain in the neck and lumbar region disappeared, the patient began to feel alert, increased activity and improved mood. Retrospectively, epilepsy and migraine attacks are rare, chronic tension headaches and nonspecific chronic neck and back pain are also rare.
Conclusion. The present clinical example is illustrative, as it demonstrates the appropriateness and relative efficacy of osteopathic treatment in a particular patient with several chronic diseases of the nervous system.
About the Authors
G. M. MusinaRussian Federation
Gulisa M. Musina, Cand. Sci. (Med.), Assistant Professor at the Department of Neurosurgery and Medical Rehabilitation; Assistant Professor at the Department of Neurology
Scopus Author ID: 59012113000
bld. 3 ul. Lenina, Republic Bashkortostan, Ufa, Russia 450008
bld. 10 ul. Studentskaya, Voronezh, Russia 394036
Yu. O. Novikov
Russian Federation
Yuriy О. Novikov, Dr. Sc. (Med.), Professor, Professor at the Department of Neurosurgery and Medical Rehabilitation
Scopus Author ID: 7202658565
bld. 3 ul. Lenina, Republic Bashkortostan, Ufa, Russia 450008
S. M. Musina
Russian Federation
Sofia M. Musina, 6th year medical student
bld. 3 ul. Lenina, Republic Bashkortostan, Ufa, Russia 450008
References
1. Drapkina O. M., Shutov A. M., Efremova E. V. Comorbidity, multimorbidity, dual diagnosis — synonyms or different concepts? Kardiovaskuliarnaya terapiya i profi laktika. 2019; 18 (2): 65–69. https://doi.org/10.15829/1728-8800-2019-2-65-69 (in russ.).
2. Potekhina Yu. P., Tregubova E. S., Mokhov D. E. Effects of osteopathic correction and the possibility of their study. Russ. Osteopath. J. 2022; 4: 8–29. https://doi.org/10.32885/2220-0975-2022-4-8-29 (in russ.)
3. Belash V. O., Mokhov D. E., Tregubova E. S. Osteopathic correction in complex therapy and rehabilitation of patients with vertebral artery syndrome. Vopr. kurortol., fi zioter. i LFK. 2018; 95 (6): 34–43 (in russ.).
4. Musina G. M., Kushkov A. A., Mukhin K. J. Osteopathic correction effect on anxiety and depression level according to HADS scale in children with various forms of epilepsy. Russ. Osteopath. J. 2018; 3–4: 87–97. https://doi.org/10.32885/2220-0975-2018-3-4-87-97 (in russ.).
5. Jara Silva C. E., Joseph A. M., Khatib M. et al. Osteopathic manipulative treatment and the management of headaches: A scoping review. Cureus. 2022; 14 (8): e27830. https://doi.org/10.7759/cureus.27830
6. Lehnertz H., Broehl T., Rings T. et al. Modifying functional brain networks in focal epilepsy by manual visceral-osteopathic stimulation of the vagus nerve at the abdomen. Front Netw Physiol. 2023;3:1205476. https://doi.org/10.3389/fnetp.2023.1205476
7. Clinical guidelines: Epilepsy and epileptic status in adults and children. M.; 2023. https://cr.minzdrav.gov.ru/previewcr/741_1 (in russ.).
8. Mokhov D. E., Belash V. O., Aptekar I. A., Nenashkina E. N., Potekhina Yu. P., Tregubova E. S., Belyaev A. F. Somatic dysfunction: Clinical guidelines 2023. Russ. Osteopath. J. 2023; 2: 8–90. https://doi.org/10.32885/2220-0975-2023-2-8-90 (in russ.).
9. Mokhov D. E., Maryanovich A. T. Osteopathy as evidence-based medicine. Russ. Osteopath. J. 2013; 1–2:138–154 (in russ.).
10. Andreev V. V., Akhmetsafi n A. N., Akhmetsafi n S. A., Kodzaev Yu. K. Cranioneurology: defi nition, anatomical, functional and clinical aspects: A manual for doctors. St. Petersburg: Biotechnos; 2023: 166 p. (in russ.).
11. Hyung J. W., Son B. C. Generalized extension of referred trigeminal pain due to greater occipital nerve entrapment. Case Rep. Neurol. Med. 2023; 2023: 1099222. https://doi.org/10.1155/2023/1099222
12. Wang M. M., Haveles C. S., Zukotynski B. K. et al. The 27 facial sutures: timing and clinical consequences of closure. Plast. Reconstr. Surg. 2022; 149 (3): 701–720. https://doi.org/10.1097/PRS.0000000000008816
13. Roth D. M., Souter K., Graf D. Craniofacial sutures: Signaling centres integrating mechanosensation, cell signaling, and cell differentiation. Europ. J. Cell Biol. 2022; 3 (101): 151258. https://doi.org/10.1016/j.ejcb.2022.151258
14. White H. E., Goswami A., Tucker A. S. The Intertwined evolution and development of sutures and cranial morphology. Front Cell. Dev. Biol. 2021; 9: 653579. https://doi.org/10.3389/fcell.2021.653579
15. Herring S. W. Mechanical infl uences on suture development and patency. Front Oral Biol. 2008; 12: 41–56. https://doi.org/10.1159/0000115031
16. Shiryaeva E. E., Potekhina Yu. P., Gaivoronskiy I. V. et al. Osteopathy. Somatic dysfunctions of the head and dura mater region / Ed. D. E. Mokhov. M.: GEOTAR-Media; 2023: 448 p. https://doi.org/10.33029/9704-7037-4DRG-2023-1-448 (in russ.).
17. Nauman E. A., Talavage T. M., Auerbach P. S. Mitigating the consequences of subconcussive head injuries. Ann. Rev. Biomed. Eng. 2020; 22: 387–407. https://doi.org/10.1146/annurev-bioeng-091219-053447
18. Harte S. E., Harris R. E., Clauw D. J. The neurobiology of central sensitization. Journal of Applied Biobehavioral Research. Special Iss. Central Sensitiz. 2018; 2 (23): e12137. https://doi.org/10.1111/jabr.12137
19. Sessle B. J. Chronic orofacial pain: models, mechanisms, and genetic and related environmental infl uences. Int. J. Molec. Sci. 2021; 22 (13): 7112. https://doi.org/10.3390/ijms22137112
20. Gerasimova L. P., Novikov Yu. O., Orekhova L. Yu. Orofacial pain. An interdisciplinary approach: National guidelines. M.: GEOTAR-Media; 2025: 512 p. (in russ.).
21. Ganesan A., Kumar G., Gauthaman J. et al. Exploring the relationship between psychoneuroimmunology and oral diseases: A comprehensive review and analysis. J. Lifestyle Med. 2024; 14 (1): 13–19. https://doi.org/10.15280/jlm.2024.14.1.13.
22. Kuznetsova I. V. Prevention and therapy of gestational complications associated with endothelial dysfunction. Med. Alphabet. Modern gynecol. 2018; 22 (3) (in russ.).
23. Grebneva O. S., Zilber M. Yu., Volkova A. A. Debatable issues of the pathogenesis of premature placental abruption (literary review). Sci. Rev. Med. Sci. 2016; 2: 33–42 (in russ.).
24. Slater A. M., Barclay S. J., Granfar R. M.S., Pratt R. L. Fascia as a regulatory system in health and disease. Front. Neurol. 2024; 15: 1458385. https://doi.org/10.3389/fneur.2024.1458385
25. Plaut S. Long COVID-19 and viral «fi bromyalgia-ness»: Suggesting a mechanistic role for fascial myofi broblasts (Nineveh, the shadow is in the fascia). Front. Med. (Lausanne). 2023; 10: 952278. https://doi.org/10.3389/fmed.2023.952278
26. Novikov Yu. О., Akopyan A. P., Amig F. A. Multidisciplinary approach in the treatment of chronic tension headache on the background of COVID-19. Russ. Osteopath. J. 2022; 3: 114–130. https://doi.org/10.32885/2220-0975-2022-3-114-130 (in russ.).
Review
For citations:
Musina G.M., Novikov Yu.O., Musina S.M. Is osteopathic treatment appropriate for a patient with multimorbidity? Russian Osteopathic Journal. 2025;(3):123-133. (In Russ.) https://doi.org/10.32885/2220-0975-2025-3-123-133