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Results of osteopathic correction in children and adolescents with undifferentiated connective tissue dysplasia

https://doi.org/10.32885/2220-0975-2022-1-49-59

Abstract

Introduction. The syndrome of undifferentiated connective tissue dysplasia (UCTD) combines a group of diseases that is heterogeneous in origin and polymorphic in clinical manifestations. UCTD is characterized by joint hypermobility and pain in the joints and back. In the last decade, osteopathic methods for the diagnosis and correction of dorsalgia and joint mobility disorders, including UCTD, have become widespread. However, the results of osteopathic correction in children and adolescents with undifferentiated dysplasia have not yet been fully investigated.
The aim of the study was to research the results of osteopathic correction in children and adolescents with the syndrome of undifferentiated connective tissue dysplasia.
Materials and methods. The study involved 48 children and adolescents aged 10 to 18 years. A study group and a control group were formed by the simple randomization method. Each group consisted of 24 participants: 5 boys and 19 girls in the main group; 7 boys and 17 girls in the control. The participants of the main group received osteopathic correction. The participants in the control group received drug therapy and lifestyle correction. In both groups, osteopathic status, intensity of pain syndrome, functioning of the autonomic nervous system (the predominance of sympathetic or parasympathetic influences on the cardiovascular system), the level of depression and anxiety were assessed before and after the treatment.
Results. Osteopathic correction in children and adolescents with UCTD was accompanied by a statistically significant (p<0,05) decrease in the detection frequency of regional somatic dysfunctions of the head, neck, thoracic region, and pelvis. There was also a statistically significant (p<0,05) decrease in the intensity of pain syndrome, normalization of the functioning of the autonomic nervous system, which manifested in the achievement of a state of autonomic balance, assessed by the Kerdo index, a decrease in the level of depression and anxiety. Standard treatment, including drug therapy and lifestyle correction, was accompanied by the normalization of the functioning of the autonomic nervous system and a decrease in the level of depression. However, osteopathic correction led to statistically significantly more pronounced results for these indicators compared to the results of standard treatment.
Conclusion. The obtained results make it possible to consider the possibility of including osteopathic correction in the complex treatment of children and adolescents suffering from undifferentiated connective tissue dysplasia, since it have a positive effect on the course of the main disease. It is advisable to conduct a study on a larger sample of patients with subsequent follow-up assessment.

About the Authors

K. R. Valiev
«Medical Center on Minskaya»
Russian Federation

Kamil R. Valiev, osteopathic physician, neurologist 

bld. 26a ul. Minskaya, Kazan, 420140



I. Kh. Vildanov
Alekseevskaya Central District Hospital
Russian Federation

Ilnar Kh. Vildanov, chief physician 

bld. 85 ul. Kuibysheva, Republic of Tatarstan, Alekseevsky district, urban settlement Alekseevskoye, 422900



R. R. Zyatdinov
Vysokogorsk Central Regional Hospital
Russian Federation

Ramil R. Zyatdinov, chief physician 

bld. 3 ul. Zelenaya, Republic of Tatarstan, Vysokogorsky district, railway station Vysokogorsk, 422700



I. R. Gainullin
«Gainullin Clinic of Osteopathy»; Institute of Osteopathy
Russian Federation

Ildar R. Gainullin, Cand. Sci. (Med.), osteopathic physician, neurologist; assistant 

bld. 1 ul. Komsomolskaya, Kazan, 420066

bld. 1A ul. Degtyarnaya, Saint-Petersburg, 191024



References

1. Казанбаева А. В. Легостина В. А., Ганеева Е. Р. Дисплазия соединительной ткани. Международный студенческий науч. вестн. 2018; 4: 252–256. Ссылка активна на 01.09.2021. [Kazanbaeva A. V. Legostina V. A., Ganeeva E. R. Connective tissue dysplasia. Mezhdunar. stud. nauch. vestn. 2018; 4: 252–256. Accessed in September 01, 2021 (in russ.)]. https://s.eduherald.ru/pdf/2018/4-2/18507.pdf

2. Кадурина Т. И., Аббакумова Л. Н. Дисплазия соединительной ткани: путь к диагнозу. Вестн. Ивановской мед. акад. 2014; 19 (3): 5–11. [Kadurina T. I., Abbakumova L. N. Connective tissue dysplasia: way to diagnosis. Bull. Ivanovo Med. Acad. 2014; 19 (3): 5–11 (in russ.)].

3. Евтушенко С. К., Лисовский Е. В., Евтушенко О. С. Дисплазия соединительной ткани в неврологии и педиатрии: Рук. для врачей. Донецк: Издательский дом «Заславский»; 2009; 361 с. [Evtushenko S. K., Lisovskiy E. V., Evtushenko O. S. Connective tissue dysplasia in neurology and pediatrics: A guide for doctors. Donetsk: Zaslavsky Publishing House; 2009; 361 p. (in russ.)].

4. Нестеренко З. В. Дисплазия соединительной ткани — медико-социальный феномен XXI века. Боль. Суставы. Позвоночник. 2012; 1 (05): 17–23. [Nesterenko Z. V. Connective tissue dysplasia is a medical and social phenomenon of the XXI century. Pain. Joints. Spine. 2012; 1 (05): 17–23 (in russ.)].

5. Нечаева Г. И., Друк И. В., Гольтяпин В. В. Выявление и тактика ведения пациентов с недифференцированной дисплазией соединительной ткани: Методические рекомендации для врачей. М.; 2011; 52 с. [Nechaeva G. I., Druk I. V., Goltyapin V. V. Identifi cation and management of patients with undifferentiated connective tissue dysplasia: Guidelines for doctors. M.; 2011; 52 p. (in russ.)].

6. Дедова В. О., Доценко Н. Я., Боев С. С., Шехунова И. А., Герасименко Л. В. Распространенность дисплазии соединительной ткани. Медицина и образование в Сибири. 2011; (2). Ссылка активна на 01.09.2021. [Dedova V. O., Dotsenko N. Ya., Boev S. S., Shekhunova I. A., Gerasimenko L. V. Prevalence of connective tissue dysplasia (review). Medicine and Education in Siberia. 2011; (2). Accessed in September 01, 2021 (in russ.)]. https://mos.ngmu.ru/article/pdf.php?id=478

7. Абдрахманова М. Г., Епифанцева Е. В. Актуальные вопросы изучения дисплазии соединительной ткани в аспекте неврологии // В сб.: Наука и образование: проблемы и тенденции развития: Материалы Международной научнопрактической конференции. М.; 2013: 98–102. [Abdrakhmanova M. G., Epifantseva E. V. Topical issues of studying connective tissue dysplasia in the aspect of neurology // In: Science and education: problems and development trends: Materials of the International Scientifi c and Practical Conference. M.; 2013: 98–102 (in russ.)].

8. Дисплазия соединительной ткани: Клинические рекомендации. М.; 2017; 181 с. [Connective tissue dysplasia: Clinical guidelines. M.; 2017; 181 p. (in russ.)].

9. Потехина Ю. П. Структура и функции коллагена. Российский остеопатический журнал. 2016; 1–2: 87–99. [Potekhina Yu. P. Collagen Structure and Function. Russian Osteopathic Journal. 2016; 1–2: 87–99 (in russ.)]. https://doi.org/10.32885/2220-0975-2016-1-2-87-99

10. Потехина Ю. П. Роль соединительной ткани в организме. Российский остеопатический журнал. 2015; 3–4: 92–104. [Potekhina Yu. P. Role of Connective Tissue in the Body. Russian Osteopathic Journal. 2015; 3–4: 92–104 (in russ.)]. https://doi.org/10.32885/2220-0975-2015-3-4-92-104

11. Потехина Ю. П., Мохов Д. Е., Трегубова Е. С. Этиология и патогенез соматических дисфункций. Клин. патофизиол. 2017; 23 (4): 16–26. [Potekhina Yu. P., Mokhov D. E., Tregubova E. S. Etiology and pathogenesis of somatic dysfunctions. Clin. Pathophysiol. 2017; 23 (4): 16–26 (in russ.)]. https://doi.org/10.32885/2220-0975-2016-3-4-91-104

12. Мохов Д. Е., Трегубова Е. С., Потехина Ю. П. Патогенез локальных соматических дисфункций (научный обзор). Проф. и клин. мед. 2017; 1 (62): 54–59. [Mokhov D. E., Tregubova E. S., Potekhina Yu. P. Pathogenesis of the local somatic dysfunctions (scientifi c review). Prev. clin. Med. 2017; 1 (62): 54–59 (in russ.)].

13. Мохов Д. Е., Аптекарь И. А., Белаш В. О., Литвинов И. А., Могельницкий А. С., Потехина Ю. П., Тарасов Н. А., Тарасова В. В., Трегубова Е. С., Устинов А. В. Основы остеопатии: Учеб. для ординаторов. М.: ГЭОТАР-Медиа; 2020; 400 с. [Mokhov D. E., Aptekar I. A., Belash V. O., Litvinov I. A., Mogelnitsky A. S., Potekhina Yu. P., Tarasov N. A., Tarasova V. V., Tregubova E. S., Ustinov A. V. The basics of osteopathy: A textbook for residents. M.: GEOTAR-Media; 2020; 400 p. (in russ.)].

14. Gatchel R. J., McGeary D. D., McGeary C. A., Lippe B. Interdisciplinary chronic pain management: past, present, and future. Amer. Psychol. 2014; 69 (2): 119–130. https://doi.org/10.1037/a0035514

15. Scott J., Huskisson E. C. Graphic representation of pain. Pain. 1976; 2 (2): 175–184. https://doi.org/10.1016/0304-3959(76)90113-5

16. Вагин Ю. Е., Деунежева С. М., Хлытина А. А. Вегетативный индекс Кердо: роль исходных параметров, области и ограничения применения. Физиология человека. 2021; 47 (1): 31–42. [Vaguinea Yu. E., Deunezhewaa S. М., Khlytinaa A. A. Kerdo Vegetative Index: Role of Initial Parameters, Areas and Limitations of Application. Hum. Physiol. 2021; 47 (1): 31–42 (in russ.)].

17. Смулевич А. Депрессии в общей медицине: Рук. для врачей. М.: МИА; 2007; 252 с. [Smulevich A. B. Depression in General Medicine: A Guide for Physicians. M.: MIA; 2007; 252 p. (in russ.)].

18. Мохов Д. Е., Белаш В. О., Кузьмина Ю. О., Лебедев Д. С., Мирошниченко Д. Б., Трегубова Е. С., Ширяева Е. Е., Юшманов И. Г. Остеопатическая диагностика соматических дисфункций: Клинические рекомендации. СПб.: Невский ракурс; 2015; 90 с. [Mokhov D. E., Belash V. O., Kuzmina Ju. O., Lebedev D. S., Miroshnichenko D. B., Tregubova E. S., Shirjaeva E. E., Yushmanov I. G. Osteopathic Diagnosis of Somatic Dysfunctions: Clinical Recommendations. St. Petersburg: Nevskij rakurs; 2015; 90 p. (in russ.)].

19. Аптекарь И. А., Егорова И. А., Кузьмина Ю. О., Мохова Е. С., Трегубова Е. С. Остеопатическая диагностика соматических дисфункций в педиатрии: Клинические рекомендации. СПб.: Невский ракурс; 2015; 60 с. [Aptekar I. A., Egorova I. A., Kuzmina Yu. O., Mokhova E. S., Tregubova E. S. Osteopathic diagnosis of somatic dysfunctions in pediatrics: Clinical guidelines. St. Petersburg: Nevskij rakurs; 2015; 60 p. (in russ.)].

20. Правдюк Н. Г., Шостак Н. А. Гипермобильный синдром: клинические проявления, дифференциальный диагноз, подходы к терапии. Рациональная фармакотерапия в кардиологии. 2008; (3): 70–75. [Pravdyuk N. G., Shostak N. A. Hypermobility syndrome: clinical manifestations, differential diagnosis, therapy approaches. Ration. Pharmacother. Card. 2008; (3): 70–75 (in russ.)].

21. Давыдов О. С. Хронизация боли: факторы риска, механизмы и возможности предупреждения. Леч. врач. 2017; (05). Ссылка активна на 01.09.2021. [Davydov O. S. Pain chronization: risk factors, mechanisms and possibilities for prevention. Lech. Vrach. 2017; (05). Accessed in September 01, 2021 (in russ.)]. https://www.lvrach.ru/2017/05/15436717

22. Schander A., Downey H. F., Hodge L. M. Lymphatic pump manipulation mobilizes infl ammatory mediators into lymphatic circulation. Exp. biol. Med (Maywood). 2012; 237 (1): 58–63. https://doi.org/10.1258/ebm.2011.011220

23. Teodorczyk-Injeyan J. A., Injeyan H. S., Ruegg R. Spinal manipulative therapy reduces infl ammatory cytokines but not substance P production in normal subjects. J. Manipulat. Physiol. Ther. 2006; 29 (1): 14–21. https://doi.org/10.1016/j.jmpt.2005.10.002

24. Walkowski S., Singh M., Puertas J., Pate M., Goodrum K., Benencia F. Osteopathic manipulative therapy induces early plasma cytokine release and mobilization of a population of blood dendritic cells. PLoS One. 2014; 9 (3): e90132. https://doi.org/10.1371/journal.pone.0090132

25. Bordoni B., Zanier E. Understanding Fibroblasts in Order to Comprehend the Osteopathic Treatment of the Fascia. Evid Based Compl. Alternat. Med. 2015; 2015: 860934. https://doi.org/10.1155/2015/860934

26. Potekhina Yu. P., Tregubova E. S., Mokhov D. E. Osteopathy is a new medical specialty. Assessment of clinical effectiveness of osteopathic manipulative therapy in various diseases. Med. News North Caucas. 2018; 13 (3): 560–565. https://doi.org/10.14300/mnnc.2018.13105

27. Потехина Ю. П., Трегубова Е. С., Мохов Д. Е. Феномен соматической дисфункции и механизмы действия остеопатического лечения. Мед. вестн. Северного Кавказа. 2020; 15 (1): 145–152. [Potekhina Yu. P., Tregubova E. S., Mokhov D. E. The phenomenon of somatic dysfunction and the mechanisms of osteopathic treatment. Med. News North Caucasus. 2020; 15 (1): 145–152 (in russ.)]. https://doi.org/10.14300/mnnc.2020.15036

28. Мохов Д. Е., Трегубова Е. С., Потехина Ю. П. Остеопатия и ее восстановительный потенциал. СПб.: Невский ракурс; 2020; 200 с. [Mokhov D. E., Tregubova E. S., Potekhina Yu. P. Osteopathy and its regenerative potential. St. Petersburg: Nevskij rakurs; 2020; 200 p.].

29. Tomasek J., Gabbiani G., Hinz B., Chaponnier C., Brown R. A. Myofi broblasts and mechano-regulation of connective tissue remodelling. Nat. Rev. Molec. Cell Biol. 2002; 3: 349–363. https://doi.org/10.1038/nrm809

30. Gatchel R. J., Peng Y. B., Peters M. L., Fuchs P. N., Turk D. C. The biopsychosocial approach to chronic pain: Scientifi c advances and future directions. Psychol. Bull. 2007; 133 (4): 581–624. https://doi.org/10.1037/0033-2909.133.4.581

31. Себастьян-Раузелл Дж. М., Мартинес-Гарсия А. Б., Хауме-Ллинас А. С., Эскобио-Прието И. Влияние вертебральных манипуляций на вегетативную нервную систему. Российский остеопатический журнал. 2021; 3: 106–120. [Sebastian Rausell J. M., Martinez Garcia A. B., Jaume Llinas A. S., Escobio Prieto I. Infl uence of vertebral manipulations on the autonomic nervous system. Russian Osteopathic Journal. 2021; 3: 106–120 (in russ.)]. https://doi.org/10.32885/2220-0975-2021-3-106-120


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For citations:


Valiev K.R., Vildanov I.Kh., Zyatdinov R.R., Gainullin I.R. Results of osteopathic correction in children and adolescents with undifferentiated connective tissue dysplasia. Russian Osteopathic Journal. 2022;(1):49-59. (In Russ.) https://doi.org/10.32885/2220-0975-2022-1-49-59

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ISSN 2220-0975 (Print)
ISSN 2949-3064 (Online)