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<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rojournal</journal-id><journal-title-group><journal-title xml:lang="ru">Российский остеопатический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Osteopathic Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2220-0975</issn><issn pub-type="epub">2949-3064</issn><publisher><publisher-name>All-Russian Public Organization «Russian Osteopathic Association» (ROsA)</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.32885/2220-0975-2025-3-134-150</article-id><article-id custom-type="elpub" pub-id-type="custom">rojournal-704</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Физиологическое обоснование влияния механических воздействий на внутренние органы (обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>Physiological substantiation of the effect of mechanical impact on internal organs (literature review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8895-6899</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ихлеф</surname><given-names>А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ikhlef</surname><given-names>A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Адам Ихлеф, ассистент кафедры превентивной медицины, врач-остеопат</p><p>107113, Москва, ул. 3-я Рыбинская, д. 18, стр. 19 </p></bio><bio xml:lang="en"><p>Ikhlef Adam, Assistant of the Department of Preventive Medicine, osteophatic physician</p><p>bld. 18 str. 19 ul. 3rd Rybinskaya, Moscow, Russia 107113 </p></bio><email xlink:type="simple">adam.ikh.on@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8674-5633</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Потехина</surname><given-names>Ю. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Potekhina</surname><given-names>Yu. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юлия Павловна Потехина, профессор, докт. мед. наук, профессор кафедры нормальной физиологииим. Н. Ю. Беленкова; заместитель директора по научно-методической работеScopus Author ID: 55318321700</p><p>191024, Санкт-Петербург, ул. Дегтярная, д. 1, лит. А603005, Нижний Новгород, пл. Минина и Пожарского, д. 10/1 </p></bio><bio xml:lang="en"><p>Yulia P. Potekhina, professor, Dr. Sci. (Med.), Professor at the N. Yu. BelenkovDepartment of Normal Physiology; Deputy Director for Scientifi c and Methodological WorkScopus Author ID: 55318321700</p><p>bld. 1 lit. A ul. Degtyarnaya, Saint-Petersburg, Russia 191024bld. 10/1 pl. Minin and Pozharskiy, Nizhniy Novgorod, Russia 603005 </p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0003-9352-8049</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сименко</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Simenko</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Екатерина Владимировна Сименко, врач-невролог</p><p>119048, Москва, ул. Трубецкая, д. 8, стр. 2 </p></bio><bio xml:lang="en"><p>Ekaterina V. Simenko, neurologist</p><p>bld. 8 k. 2 ul. Trubetskaya, Moscow, Russia 119048</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Институт междисциплинарной медицины</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute of Interdisciplinary Medicine</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Институт остеопатии;&#13;
Приволжский исследовательский медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institution of Osteopathy;&#13;
Privolzhskiy Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Первый Московский государственный медицинский университет им. И. М. Сеченова (Сеченовский университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov First Moscow State Medical University (Sechenovskiy University)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>18</day><month>09</month><year>2025</year></pub-date><volume>0</volume><issue>3</issue><fpage>134</fpage><lpage>150</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ихлеф А., Потехина Ю.П., Сименко Е.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Ихлеф А., Потехина Ю.П., Сименко Е.В.</copyright-holder><copyright-holder xml:lang="en">Ikhlef A., Potekhina Y.P., Simenko E.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://rojournal.elpub.ru/jour/article/view/704">https://rojournal.elpub.ru/jour/article/view/704</self-uri><abstract><p>Актуальность данной статьи обусловлена стремлением расширить представление о влиянии соматической дисфункции (СД) на работу внутренних органов и о возможных механизмах действия остеопатической коррекции. Цель данного обзора — продемонстрировать взаимосвязь изменений в архитектонике соединительной ткани и биомеханических процессов с одной стороны и функционирования внутренних органов и систем и развитием в них патологии с другой. Приведены данные исследований, посвященных механосенситивности клеток различных органов и тканей, обусловленных в первую очередь работой механочувствительных ионных каналов (пьезоканалов). Рассмотрены изменения функционирования и развитие патологических процессов, обусловленных механическими воздействиями на органы пищеварительной, сердечно-сосудистой, мочеполовой, дыхательной и нервной систем. Высказаны предположения о взаимосвязи СД и регуляторных процессов во внутренних органах и нервной системе, которые требуют дальнейшего изучения. Понимание того, как СД влияет на эти процессы, может существенно обогатить наше знание о терапевтическом воздействии остеопатического лечения и других физических методов, а также их потенциале в профилактике различных заболеваний.</p></abstract><trans-abstract xml:lang="en"><p>The relevance of this article is due to the desire to expand the understanding of osteopathic methods of treatment, which, according to the principles of osteopathic medicine, can not only improve the function of the musculoskeletal system, but also positively affect the work of internal organs, contributing to the prevention of their diseases. The data of studies devoted to the mechanosensitivity of cells of various organs and tissues, primarily due to the work of mechanosensitive ion channels (piezo channels), are presented. Despite the accumulated knowledge of the clinical manifestations of somatic disfunction, the relationship of these disorders to plastic and regulatory changes in visceral organs requires further investigation. Understanding how somatic disfunction affects these processes may significantly enrich our knowledge of the therapeutic effects of osteopathic treatment and other physical modalities, as well as their potential in the prevention of various diseases.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>механочувствительность</kwd><kwd>механотрансдукция</kwd><kwd>соматическая дисфункция</kwd><kwd>соединительная ткань</kwd><kwd>механочувствительные ионные каналы</kwd><kwd>внутренние органы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>mechanosensitivity</kwd><kwd>mechanotransduction</kwd><kwd>somatic dysfunction</kwd><kwd>connective tissue</kwd><kwd>mechanosensitive ion channels</kwd><kwd>internal organs</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Потехина Ю. П., Гуричев А. А. Терминология повреждений в остеопатии и в других медицинских дисциплинах. 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