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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rojournal</journal-id><journal-title-group><journal-title xml:lang="ru">Российский остеопатический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Osteopathic Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2220-0975</issn><issn pub-type="epub">2949-3064</issn><publisher><publisher-name>All-Russian Public Organization «Russian Osteopathic Association» (ROsA)</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.32885/2220-0975-2020-1-2-168-179</article-id><article-id custom-type="elpub" pub-id-type="custom">rojournal-215</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Синдром Зудека — современные представления о патогенезе, факторах риска, диагностике и лечении (обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>Sudeck syndrome — current understanding of pathogenesis, risk factors, diagnosis and treatment (literature review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Михнов</surname><given-names>Г. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Mikhnov</surname><given-names>G. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-остеопат,</p><p>Самара</p></bio><bio xml:lang="en"><p>osteopathic physician,</p><p>Samara</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7031-4644</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мирошниченко</surname><given-names>Д. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Miroshnichenko</surname><given-names>D. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ассистент Института остеопатии,</p><p>199034 Санкт-Петербург, Университетская наб., д.7/9</p></bio><bio xml:lang="en"><p>assistant of the Institute of Osteopathy,</p><p>bld. 7/9 Universitetskaya nab., Saint-Petersburg, 199034</p></bio><email xlink:type="simple">dmitrii.miroshni@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Центр остеопатии доктора Коваленко</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Center for Osteopathy of Dr. Kovalenko</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Санкт-Петербургский государственный университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Saint-Petersburg State University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>06</day><month>06</month><year>2020</year></pub-date><volume>0</volume><issue>1-2</issue><fpage>168</fpage><lpage>179</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Михнов Г.И., Мирошниченко Д.Б., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Михнов Г.И., Мирошниченко Д.Б.</copyright-holder><copyright-holder xml:lang="en">Mikhnov G.I., Miroshnichenko D.B.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://rojournal.elpub.ru/jour/article/view/215">https://rojournal.elpub.ru/jour/article/view/215</self-uri><abstract><p>Одним из серьезных осложнений после травм конечностей является развитие синдрома Зудека–Турнера (рефлекторная симпатическая дистрофия). Частота развития этой патологии в последнее время увеличилась и составляет, по разным литературным источникам, 5–40 %. Патология носит прогрессирующий характер, сопровождающийся хроническим болевым синдромом, нарушением функции конечности, трофическими расстройствами, постепенной деформацией конечности, развитием остеопороза, развитием тугоподвижности расположенных рядом суставов и нередко заканчивается инвалидизацией. Пациенты этой группы длительное время находятся на лечении (до 4–6 мес и более после снятия иммобилизации). Применяют различные методы консервативного лечения: медикаментозное, физиотерапию, ЛФК, блокады, а при длительной и безуспешной консервативной терапии — различные виды оперативных способов. Но даже при применении всего комплекса современного лечения исход бывает неблагоприятный — развивается контрактура. Тяжесть и длительность заболевания, низкая эффективность лечения, непредсказуемость исхода патологического процесса заставляют травматологов искать новые методики лечения.</p></abstract><trans-abstract xml:lang="en"><p>One of the serious complications after limb injuries is the development of Sudeck–Turner syndrome (refl ex sympathetic dystrophy). The pathology development frequency has recently increased, and varies, according to various literary sources, from 5 to 40 %. The pathology has a progressing nature, and is accompanied by chronic pain, impaired limb function, trophic disorders, gradual deformation of the limb, the development of osteoporosis, stiffness of adjacent joints, and often ends with the patient disability. Patients of this category have a long time treatment (up to 4–6 or more months after removal of immobilization). Various methods of conservative treatment are used: drug therapy, physiotherapy, exercise therapy, blockade, and finally with prolonged and unsuccessful conservative therapy, various types of surgical techniques. But even for the entire complex of modern treatment methods applying the outcome could be unfavorable - contracture develops. So the severity and duration of the disease, the treatment low efficiency, the unpredictability of the pathological process outcome forces traumatologists to look for new treatment methods.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>травмы конечностей</kwd><kwd>посттравматический болевой синдром</kwd><kwd>синдром Зудека</kwd><kwd>симпатическая дистрофия</kwd><kwd>тугоподвижность суставов</kwd><kwd>инвалидизация</kwd></kwd-group><kwd-group xml:lang="en"><kwd>limb injuries</kwd><kwd>post-traumatic pain syndrome</kwd><kwd>Sudeck syndrome</kwd><kwd>sympathetic dystrophy</kwd><kwd>joint stiffness</kwd><kwd>disability</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ортопедия: Национальное рук. / Под ред. С. П. Миронова, Г. П. Котельникова. М.: ГЭОТАР-Медиа; 2008; 820 с.</mixed-citation><mixed-citation xml:lang="en">Orthopedics: National Guide / Ed. S. P. Mironov, G. P. Kotelnikov. Moscow: GEOTAR-Media; 2008; 820 p. (in russ.).</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Кукушкин М. Л., Хитров Н. К. Общая патология боли. М.: Медицина, 2004; 144 с.</mixed-citation><mixed-citation xml:lang="en">Kukushkin M. L., Khitrov N. K. General pathology of pain. M.: Medicine, 2004; 144 p. (in russ.).</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Цымбалюк В. И., Сапон Н. А. Классификация болевых синдромов. Doctor. 2003; (1): 11–13.</mixed-citation><mixed-citation xml:lang="en">Tsymbalyuk V. I., Sapon N. A. Classification of pain syndromes. Doctor. 2003; (1): 11–13 (in russ.).</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Каменев Ю. Ф. Классификация хронических болевых синдромов (по Ю. Ф. Каменеву). Гений ортопедии. 2004; (1): 147–149.</mixed-citation><mixed-citation xml:lang="en">Kamenev Y. F. The classification of the chronic pain syndromes (according to Y. F. Kamenev).Genij Ortopedii. 2004; (1): 147–149 (in russ.).</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Данилов А. Современные подходы к лечению боли. Ссылка активна на 20.02.2020. http://medi.ru/doc/140348_3.htm.</mixed-citation><mixed-citation xml:lang="en">Danilov A. Modern approaches to the treatment of pain. Accessed February 20, 2020 (in russ.). http://medi.ru/doc/140348_3.htm</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Stanton-Hicks M., Jänig W., Hassenbusch S., Haddox J. D., Boas R., Wilson P. Reflex sympathetic dystrophy: changing concepts and taxonomy. Pain. 1995; 63 (1): 127–133. https://doi.org/10.1016/0304-3959(95)00110-e</mixed-citation><mixed-citation xml:lang="en">Stanton-Hicks M., Jänig W., Hassenbusch S., Haddox J. D., Boas R., Wilson P. Reflex sympathetic dystrophy: changing concepts and taxonomy. Pain. 1995; 63 (1): 127–133. https://doi.org/10.1016/0304-3959(95)00110-e</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Болевые синдромы в неврологической практике / Под ред. В. Л. Голубева. М.: МЕДпресс-информ; 2010; 336 с.</mixed-citation><mixed-citation xml:lang="en">Pain syndromes in neurological practice / Ed. V. L. Golubev. M.: MEDpress-inform; 2010; 336 p. (in russ.).</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Крупаткин А. И., Голубев В. Г., Берглезов М. Л., Колосов В. Л., Меркулов М. В., Юлов В. В., Зейналов В. Т. Современная концепция посттравматического комплексного регионарного болевого синдрома. 2008. Ссылка активна на 20.02.2020. http://medbe.ru/materials/travmatologiya-i-ortopediya-obshchee/sovremennaya-kontseptsiya-posttravmaticheskogo-kompleksnogo-regionarnogobolevogo-sindroma</mixed-citation><mixed-citation xml:lang="en">Krupatkin A. I., Golubev V. G., Berglezov M. L., Kolosov V. L., Merkulov M. V., Yulov V. V., Zeynalov V. T. Modern concept of post-traumatic complex regional pain syndrome. Accessed February 20, 2020 (in russ.). http://medbe.ru/materials/travmatologiya-i-ortopediya-obshchee/sovremennaya-kontseptsiya-posttravmaticheskogo-kompleksnogo-regionarnogobolevogo-sindroma</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Ягджян Г. В., Абрамян Д. О., Григорян Б. Э. Синдром Зудека: комплексный регионарный болевой синдром I типа. 2004. Ссылка активна на 20.02.2020. http://www.farfaa-salzburg.am/cme/met/Sudeck.pdf</mixed-citation><mixed-citation xml:lang="en">Yagjyan G. V., Abrahamyan D. O., Grigoryan B. E. Sudeck Syndrome: A complex regional type I pain syndrome. Accessed February 20, 2020 (in russ.). http://www.farfaa-salzburg.am/cme/met/Sudeck.pdf</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Николаева Е. В., Смбатян С. М., Абхази С. Д. Синдром Зудека с позиций медицинской экспертизы. 2009. Ссылка активна на 20.02.2020. https://www.provrach.ru/article/1838-sindrom-zudeka-spozitsiy-meditsinskoy-ekspertizy</mixed-citation><mixed-citation xml:lang="en">Nikolaeva E. V., Smbatyan S. M., Abkhazi S. D. Sudeck′s syndrome from the standpoint of medical examination. Accessed February 20, 2020 (in russ.). https://www.provrach.ru/article/1838-sindrom-zudeka-spozitsiy-meditsinskoy-ekspertizy</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Иоффе Д. И. Посттравматическая рефлекторная дистрофия конечностей с позиции врача-реабилитолога (обзор литературы). Травматол. и ортопед. России. 1996; (1): 77–81.</mixed-citation><mixed-citation xml:lang="en">Ioffe D. I. Post-traumatic reflex dystrophy of the extremities from the perspective of a rehabilitologist (literature review). Traumatol. Orthoped. Russia. 1996; (1): 77–81 (in russ.).</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Прокин Б. М., Деденева Ж. Г. Некоторые аспекты медицинской реабилитации при синдроме Турнера–Зудека. Травматол. и ортопед. России. 1994. (1): 92–97.</mixed-citation><mixed-citation xml:lang="en">Prokin B. M., Dedeneva Zh. G. Some aspects of medical rehabilitation in Turner-Sudeck syndrome. Traumatol. Orthoped. Russia. 1994. (1): 92–97 (in russ.).</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Новиков А. В., Яхно Н. Н. Комплексный регионарный болевой синдром как вариант хронической нейропатической боли. Регулярные выпуски РМЖ. 2001; (25): 1152–1161.</mixed-citation><mixed-citation xml:lang="en">Novikov A. V., Yakhno N. N. Integrated regional pain syndrome as a variant of chronic neuropathic pain. Regular issues of Rus. Med. J. 2001; (25): 1152–1161 (in russ.).</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Steinbrocker O. The shoulder-hand syndrome. Amer. J. Med. 1947; 3 (4): 402–407. https://doi.org/10.1016/0002-9343(47)90170-8</mixed-citation><mixed-citation xml:lang="en">Steinbrocker O. The shoulder-hand syndrome. Amer. J. Med. 1947; 3 (4): 402–407. https://doi.org/10.1016/0002-9343(47)90170-8</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Gellman H., Nichols D. Reflex Sympathetic Dystrophy in the Upper Extremity. J. Amer. Acad. Orthopaed. Surg. 1997; 5 (6): 313–322. https://doi.org/10.5435/00124635-199711000-00003</mixed-citation><mixed-citation xml:lang="en">Gellman H., Nichols D. Reflex Sympathetic Dystrophy in the Upper Extremity. J. Amer. Acad. Orthopaed. Surg. 1997; 5 (6): 313–322. https://doi.org/10.5435/00124635-199711000-00003</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Новиков А. В., Яхно Н. Н., Алексеев В. В. Комплексный регионарный болевой синдром при поражении периферических нервов: клинические, патогенетические и терапевтические аспекты. Неврол. журн. 1999. 4 (5): 7–11.</mixed-citation><mixed-citation xml:lang="en">Novikov A. V., Yakhno N. N., Alekseev V. V. Integrated regional pain syndrome with damage to peripheral nerves: clinical, pathogenetic and therapeutic aspects. Neurol. J. 1999. 4 (5): 7–11 (in russ.).</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Золотушкин М. Л. Лечение посттравматического комплекса регионарного болевого синдрома с применением криогенных технологий и медикаментозной коррекции: Автореф. дис. канд. мед. наук. Пермь, 2012.</mixed-citation><mixed-citation xml:lang="en">Zolotushkin M. L. Treatment of post-traumatic complex of regional pain syndrome with the use of cryogenic technologies and drug correction: Abstract Diss. Cand. Sci. (Med.). Perm′, 2012 (in russ.).</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Бейдик О. В., Шоломов И. И., Ромакина Н. А., Шоломова Е. И., Голобурдин Ю. В., Спицын А. И. Способ лечения дегенеративных заболеваний опорно-двигательного аппарата и посттравматических болевых синдромов: Патент РФ на изобретение № 2274472 / 16.09.2004. https://www1.fips.ru/Archive/PAT/2006FULL/2006.04.20/DOC/RUNWC1/000/000/002/274/472/DOCUMENT.PDF</mixed-citation><mixed-citation xml:lang="en">Bejdik O. V., Sholomov I. I., Romakina N. A., Sholomova E. I., Goloburdin Ju. V., Spitsyn A. I. Method for treating patients for degenerative locomotor apparatus diseases and posttraumatic pain syndromes: Patent RF for invention 2274472 / 16.09.2004 (in russ.). https://www1.fips.ru/Archive/PAT/2006FULL/2006.04.20/DOC/RUNWC1/000/000/002/274/472/DOCUMENT.PDF</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Europ. J. Pain. 2002; 6 (suppl. B). https://doi.org/10.1002/ejp.2002.6.issue-sb</mixed-citation><mixed-citation xml:lang="en">Europ. J. Pain. 2002; 6 (suppl. B). https://doi.org/10.1002/ejp.2002.6.issue-sb</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Кукушкин М. Л. Неврогенные болевые синдромы. По материалам, опубликованным в Европейском журнале боли (European journal of Pain) в 2002 г. Боль. 2003; 1 (1): 69–70.</mixed-citation><mixed-citation xml:lang="en">Kukushkin M. L. Neurogenic pain syndromes. Based on materials published in the European Journal of Pain in 2002. Pain. 2003; 1 (1): 69–70 (in russ.).</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Forouzanfar T., Köke A. J. A., Kleef M., Weber W. E. J. Treatment of complex regional pain syndrome type I. Europ. J. Pain. 2002; 6 (2): 105–122. https://doi.org/10.1053/eujp.2001.0304</mixed-citation><mixed-citation xml:lang="en">Forouzanfar T., Köke A. J. A., Kleef M., Weber W. E. J. Treatment of complex regional pain syndrome type I. Europ. J. Pain. 2002; 6 (2): 105–122. https://doi.org/10.1053/eujp.2001.0304</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Rauck R. L., Eisenach J. C., Jackson K., Young L. D., Southern J. Epidural clonidine treatment for refractory reflex sympathetic dystrophy. Anesthesiology. 1993; 79 (6): 1163–1169. https://doi.org/10.1097/00000542-199312000-00005</mixed-citation><mixed-citation xml:lang="en">Rauck R. L., Eisenach J. C., Jackson K., Young L. D., Southern J. Epidural clonidine treatment for refractory reflex sympathetic dystrophy. Anesthesiology. 1993; 79 (6): 1163–1169. https://doi.org/10.1097/00000542-199312000-00005</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Verdugo R. J., Ochoa J. L. Sympathetically maintained pain. Neurology. 1994; 44 (6): 1003. https://doi.org/10.1212/wnl.44.6.1003</mixed-citation><mixed-citation xml:lang="en">Verdugo R. J., Ochoa J. L. Sympathetically maintained pain. Neurology. 1994; 44 (6): 1003. https://doi.org/10.1212/wnl.44.6.1003</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Blanchard J., Ramamurthy S., Walsh N., Hoffman J., Schoenfeld L. Intravenous regional sympatholysis: A double-blind comparison of guanethidine, reserpine, and normal saline. J. Pain Symptom Manag. 1990; 5 (6): 357–361. https://doi.org/10.1016/0885-3924(90)90030-n</mixed-citation><mixed-citation xml:lang="en">Blanchard J., Ramamurthy S., Walsh N., Hoffman J., Schoenfeld L. Intravenous regional sympatholysis: A double-blind comparison of guanethidine, reserpine, and normal saline. J. Pain Symptom Manag. 1990; 5 (6): 357–361. https://doi.org/10.1016/0885-3924(90)90030-n</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">McQuay H., Carroll D., Jadad A. R., Wiffen P., Moore A. Anticonvulsant drugs for management of pain: a systematic review. Brit. med. J. 1995; 311 (7012): 1047–1052. https://doi.org/10.1136/bmj.311.7012.1047</mixed-citation><mixed-citation xml:lang="en">McQuay H., Carroll D., Jadad A. R., Wiffen P., Moore A. Anticonvulsant drugs for management of pain: a systematic review. Brit. med. J. 1995; 311 (7012): 1047–1052. https://doi.org/10.1136/bmj.311.7012.1047</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Kettler R. E., Abram S. E. Intravenous regional droperidol in the management of reflex sympathetic dystrophy: a doubleblind, placebo-controlled, crossover study. Anesthesiology. 1988; 69 (6): 933–935. https://doi.org/10.1097/00000542- 198812000-00020</mixed-citation><mixed-citation xml:lang="en">Kettler R. E., Abram S. E. Intravenous regional droperidol in the management of reflex sympathetic dystrophy: a doubleblind, placebo-controlled, crossover study. Anesthesiology. 1988; 69 (6): 933–935. https://doi.org/10.1097/00000542- 198812000-00020</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Bounameaux H. M., Hellemans H., Verhaeghe R., Dequeker J. Ketanserin (5 HT2-Antagonist) in Secondary Raynaud′s Phenomenon. J. Cardiovas. Pharmacol. 1984; 6 (5): 975. https://doi.org/10.1097/00005344-198409000-00037</mixed-citation><mixed-citation xml:lang="en">Bounameaux H. M., Hellemans H., Verhaeghe R., Dequeker J. Ketanserin (5 HT2-Antagonist) in Secondary Raynaud′s Phenomenon. J. Cardiovas. Pharmacol. 1984; 6 (5): 975. https://doi.org/10.1097/00005344-198409000-00037</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Zuurmond W. W. A., Langendijk P. N. J., Bezemer P. D., Brink H. E. J., Lange J. J., Loenen A. C. Treatment of acute reflex sympathetic dystrophy with DMSO 50 % in a fatty cream. Acta Anaesthesiol. Scand. 1996; 40 (3): 364–367. https://doi.org/10.1111/j.1399-6576.1996.tb04446.x</mixed-citation><mixed-citation xml:lang="en">Zuurmond W. W. A., Langendijk P. N. J., Bezemer P. D., Brink H. E. J., Lange J. J., Loenen A. C. Treatment of acute reflex sympathetic dystrophy with DMSO 50 % in a fatty cream. Acta Anaesthesiol. Scand. 1996; 40 (3): 364–367. https://doi.org/ 10.1111/j.1399-6576.1996.tb04446.x</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Varenna M., Zucchi F., Ghiringhelli D. et al. Intravenous clodronate in the treatment of refl ex sympathetic dystrophy syndrome. A randomized, double blind, placebo controlled study. J. Rheumatol. 2000; 27 (6): 1477–1483.</mixed-citation><mixed-citation xml:lang="en">Varenna M., Zucchi F., Ghiringhelli D. et al. Intravenous clodronate in the treatment of reflex sympathetic dystrophy syndrome. A randomized, double blind, placebo controlled study. J. Rheumatol. 2000; 27 (6): 1477–1483.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Adami S., Fossaluzza V., Gatti D., Fracassi E., Braga V. Bisphosphonate therapy of reflex sympathetic dystrophy syndrome. Ann. Rheum. Dis. 1997; 56 (3): 201–204. https://doi.org/10.1136/ard.56.3.201</mixed-citation><mixed-citation xml:lang="en">Adami S., Fossaluzza V., Gatti D., Fracassi E., Braga V. Bisphosphonate therapy of reflex sympathetic dystrophy syndrome. Ann. Rheum. Dis. 1997; 56 (3): 201–204. https://doi.org/10.1136/ard.56.3.201</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Gobelet C., Meier J.-L., Schaffner W., Bischof-Delaloye A., Gerster J.-C., Burckhardt P. Calcitonin and reflex sympathetic dystrophy syndrome. Clin. Rheumatol. 1986; 5 (3): 382–388. https://doi.org/10.1007/BF02054258</mixed-citation><mixed-citation xml:lang="en">Gobelet C., Meier J.-L., Schaffner W., Bischof-Delaloye A., Gerster J.-C., Burckhardt P. Calcitonin and reflex sympathetic dystrophy syndrome. Clin. Rheumatol. 1986; 5 (3): 382–388. https://doi.org/10.1007/BF02054258</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Christensen K., Jensen E. M., Noer I. The reflex dystrophy syndrome response to treatment with systemic corticosteroids. Acta Chirurg. Scand. 1982; 148 (8): 653–655.</mixed-citation><mixed-citation xml:lang="en">Christensen K., Jensen E. M., Noer I. The reflex dystrophy syndrome response to treatment with systemic corticosteroids. Acta Chirurg. Scand. 1982; 148 (8): 653–655.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Kho K. H. The impact of acupuncture on pain in patients with reflex sympathetic dystrophy. Pain Clin. 1995; 8 (1): 59–61.</mixed-citation><mixed-citation xml:lang="en">Kho K. H. The impact of acupuncture on pain in patients with reflex sympathetic dystrophy. Pain Clin. 1995; 8 (1): 59–61.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Hord A. H., Rooks M. D., Stephens B. O., Rogers H. G., Fleming L. L. Intravenous regional bretylium and lidocaine for treatment of reflex sympathetic dystrophy: a randomized, double-blind study. Anesth. et Analg. 1992; 74 (6): 818–821. https://doi.org/10.1213/00000539-199206000-00007</mixed-citation><mixed-citation xml:lang="en">Hord A. H., Rooks M. D., Stephens B. O., Rogers H. G., Fleming L. L. Intravenous regional bretylium and lidocaine for treatment of reflex sympathetic dystrophy: a randomized, double-blind study. Anesth. et Analg. 1992; 74 (6): 818–821. https://doi.org/10.1213/00000539-199206000-00007</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Тулупов А. Н., Бесаев Г. М., Синенченко Г. И., Озеров В. Ф., Багдасарьянц В. Г. Посттравматический болевой синдром (синдром Зудека): Учеб.-метод. пособие. СПб.: Стикс; 2015; 33 с.</mixed-citation><mixed-citation xml:lang="en">Tulupov A. N., Besaev G. M., Sinenchenko G. I., Ozerov V. F., Bagdasaryan V. G. Posttraumatic pain syndrome (Sudeck′s syndrome): Educat. and methodol. guide. SPb.: Styx; 2015; 33 p. (in russ.).</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
